Topos Bio
AI drug discovery models protein dynamics and small-molecule interactions for previously difficult disease targets
Highlights
- New on EvolcAdded 2026-11-13
About Topos Bio
Topos Bio develops generative models that predict protein conformational ensembles and their interactions with small molecules. Its BioScape platform maps protein ensembles across the human proteome, while Topos-Bind models compound binding to those ensembles.
The company is building a drug discovery platform focused on intrinsically disordered proteins implicated in neurodegenerative diseases and cancer. It combines computational modeling with experimental and simulation data generated through its lab work.
Topos Bio announced a $10.5 million seed round in January 2026. Its listed openings include computational chemistry, cellular biology, and machine-learning research roles in the San Francisco area.
Product: Generative protein-modeling and drug-discovery platform for predicting conformational ensembles and small-molecule interactions.
Jobs at Topos Bio
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