Tiziana Life Sciences

Clinical-stage biotech developing intranasal and fully human antibody immunotherapies for multiple sclerosis, Alzheimer's and ALS

London, United KingdomFounded 1998tizianalifesciences.comWebsite technologies

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Highlights

  • New on EvolcAdded 2026-10-28

About Tiziana Life Sciences

Tiziana Life Sciences is a clinical-stage biotechnology company developing immunotherapies for neurodegenerative and neuroinflammatory diseases. Its lead candidate, Foralumab (TZLS-401), is a fully human anti-CD3 monoclonal antibody being developed for intranasal administration. The pipeline also includes an anti-IL-6 receptor antibody (TZLS-501) and milciclib.

The company targets non-active secondary progressive multiple sclerosis, Alzheimer's disease, ALS, multiple system atrophy and other indications. It uses a lean, virtual research and development model, relying on outside expert teams for each business function. Its clinical trials and expanded access programmes are its main activity.

Tiziana was founded in 1998 and is headquartered in London. It is listed on NASDAQ under the ticker TLSA. Recent updates include a Phase 2 trial of intranasal Foralumab in mild Alzheimer's disease and an orphan drug designation filing with the FDA for Foralumab in multiple system atrophy.

Product: Foralumab (TZLS-401), a fully human anti-CD3 monoclonal antibody for intranasal use in neurodegenerative and neuroinflammatory diseases; also anti-IL-6R mAb TZLS-501 and milciclib.

Jobs at Tiziana Life Sciences

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Leadership

  • Ivor Elrifi · Chief Executive Officer & Executive Director
  • Keeren Shah · Chief Operating Officer & Chief Financial Officer

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