Constructivebio

Designs and manufactures new-to-nature proteins and peptides for pharmaceutical and industrial partners

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Highlights

  • Hiring2 open roles
  • New on EvolcAdded 2026-10-29

About Constructivebio

Constructive Bio designs and manufactures new-to-nature proteins using an expanded genetic code. Its Syn61 recoded genome and engineered tRNAs incorporate new chemical building blocks into protein chains. Its BioForge programmable cellular manufacturing platform scales the production of complex proteins, including long-chain peptides and molecules with multiple non-canonical amino acids.

Customers are pharmaceutical and industrial partners, with whom the company develops next-generation biologics and materials. Therapeutics is its main application area. Recent partnerships include a collaboration with RxCelerate on drug design and development and a collaboration with the Ellison Institute's Generative Biology Institute in Oxford.

The company is based in Cambridge, UK, and its founder and CSO is Prof. Jason Chin, whose research group is at the MRC Laboratory of Molecular Biology. Ola Wlodek, PhD, is CEO. The team lists 60+ members, 23+ PhDs and people from 24 countries. Open positions include a part-time IT Manager on a 12-month contract.

Product: BioForge, a programmable cellular manufacturing platform for new-to-nature proteins and peptides with non-canonical amino acids, built on the Syn61 recoded genome.

Jobs at Constructivebio (2)

Constructivebio is hiring for 2 roles, mostly in operations, based in Cambridge.

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