Azadyne
Pre-clinical drug developer targeting tRNA modification pathways to treat autoimmune and other diseases
Highlights
- New on EvolcAdded 2026-11-14
About Azadyne
Azadyne is a pre-clinical drug company developing small molecules that selectively modify specific tRNAs, modulating protein synthesis in targeted cells. The company describes its approach as a platform that could apply to several disease areas, with efficacy reported in multiple models and in human samples.
Azadyne is a spin-out from Trinity College Dublin, commercialising research on the QTRT or TGT pathway from the laboratories of Profs Kelly, Connon and Southern. It was incorporated in 2018 and has received investment from VC and EIS investors, including syndicates led by NCL & Kent Life Sciences and the private equity group 24 Haymarket. It describes itself as a virtual company supported by consultants and contract research organisations.
The company is headquartered in London and has an office at Canterbury Innovation Centre in Canterbury, Kent. Its leadership includes CEO Dr Jason Rutt and a board with representatives from NCL, 24 Haymarket and Trinity College Dublin.
Product: Pre-clinical small-molecule candidates that selectively modify tRNA via the QTRT/TGT pathway, with oral bioavailability across several chemical series.
Jobs at Azadyne
Leadership
- Mike Southern · Medicinal Chemistry TCDSource: company website
- Stephen Connon · Head of Synthetic Chemistry TCDSource: company website
- Vincent Kelly · Head of TCD transgenic facility.Source: company website
- Jason Rutt · CEOSource: company website
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