Kiniksa Pharmaceuticals International, PLC

Biopharmaceutical company developing immune-modulating therapies, focused on cardiovascular diseases such as recurrent pericarditis

London, United KingdomFounded 2024kiniksa.comWebsite technologies

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Highlights

  • Young companyFounded 2024
  • New on EvolcAdded 2026-10-28

About Kiniksa Pharmaceuticals International, PLC

Kiniksa Pharmaceuticals is a biopharmaceutical company developing immune-modulating therapies, with a focus on cardiovascular diseases. Its FDA-approved product ARCALYST (rilonacept) is indicated for recurrent pericarditis. Its clinical-stage pipeline includes KPL-387, an investigational IL-1 receptor antagonist monoclonal antibody being tested in the pivotal Phase 3 PASTORALE trial in recurrent pericarditis.

The company develops therapies for patients with debilitating diseases and out-licenses and in-licenses assets with partners. These include a collaboration with Huadong Medicine for ARCALYST and mavrilimumab in the Asia Pacific region (excluding Japan) and a global license agreement with Roche and Genentech for vixarelimab.

The website dates the company's founding to 2015. The UK PLC entity was registered in London in 2024, and the company listed on the NASDAQ Global Market in 2018 after an IPO. Offices are in London, Lexington (Massachusetts, USA, listed as its USA headquarters), Zug (Switzerland) and La Jolla (California, USA).

Product: ARCALYST (rilonacept), an FDA-approved therapy for recurrent pericarditis, and investigational KPL-387 in Phase 3 development.

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