Gradient Denervation Technologies
Ultrasound catheter system for pulmonary artery denervation, aimed at patients with pulmonary hypertension
Highlights
- New on EvolcAdded 2026-11-11
About Gradient Denervation Technologies
Gradient Denervation Technologies develops the Gradient Denervation System, an ultrasound-based catheter for pulmonary artery denervation (PADN). The procedure ablates nerves around the pulmonary artery using therapeutic ultrasound energy in a minimally invasive, percutaneous approach. The technology is built on intellectual property developed at Stanford University.
The system is intended for patients with Group 2 pulmonary hypertension, particularly CpcPH, a group the company describes as having limited treatment options. The device is investigational and limited to investigational use in the United States.
The company was founded in 2019 and is headquartered in Suresnes, France. It also lists a US address in Maple Grove, Minnesota, under Gradient Therapeutics, Inc. In 2024 it received FDA approval to expand its early feasibility study, in May 2025 the system received FDA Breakthrough Designation, and in June 2025 the company was accepted into the FDA's Total Product Life Cycle Advisory Program.
Product: Gradient Denervation System, an investigational ultrasound-based catheter platform for percutaneous pulmonary artery denervation.
Jobs at Gradient Denervation Technologies
Leadership
- Swami Gnanashanmugam · Observer/FounderSource: company website
- Martin Grasse · Chief Executive OfficerSource: company website
- David Amaoua · Chief Technology OfficerSource: company website
- Greg Mann · Chief Financial OfficerSource: company website
- Julie Messer · Chief Operating OfficerSource: company website
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Website technologies
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Website detection does not establish a paid subscription or company-wide use. Tools loaded after consent or sign-in may be missed. “No longer observed” does not prove the company stopped using a tool.