Gearbox Biosciences

Antibiotic-free plasmid DNA and recombinant protein production technology for biopharma and research partners

Tartu, EstoniaFounded 2021gearbox.bio Website technologies

Highlights

New on EvolcAdded 2026-10-29

About Gearbox Biosciences

Gearbox Biosciences develops Pop-Out-Plasmid technology for E. coli, supporting plasmid DNA and recombinant protein production without antibiotic selection. Its platform also provides stable template plasmids for long poly(A) mRNA therapeutics.

The company offers its technology for licensing and works with partners on research and development collaborations. Its applications include gene therapy, vaccines, and other therapeutic production.

Gearbox Biosciences is a University of Tartu spin-off founded in 2021 and headquartered in Tartu, Estonia. It announced a strategic collaboration with WACKER in 2025 to advance plasmid DNA manufacturing technologies.

Product: Pop-Out-Plasmid technology and licensing for antibiotic-free plasmid DNA and recombinant protein production in E. coli.

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