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Cellectis

Genome engineering biotech developing in vivo gene-editing therapies for severe lipid disorders

Paris, FranceFounded 2000cellectis.comWebsite technologies

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Highlights

  • New on EvolcAdded 2026-10-28

About Cellectis

Cellectis is a genome engineering company developing genetic medicines. Its TALEN gene-editing platform is the basis of its work, and the company has announced a strategic shift toward in vivo gene editing. Its two lead candidates are HEAL-101, a TALE-based editor for the APOC3 gene for patients with severe hypertriglyceridemia, and HEAL-201, a TALE-epigenetic modulator for the PCSK9 gene for patients with severe hypercholesterolemia. Both are formulated in lipid nanoparticles.

Cellectis has collaborations with biotechnology and pharmaceutical companies, including AstraZeneca, Servier, Allogene and Iovance, applying its genome engineering expertise across cell therapy and genetic medicine.

The company was founded in 2000 and is headquartered in Paris. It is listed and reports its financial results and SEC filings to investors. Its September 2026 announcement described the transformation into an in vivo gene editing company.

Product: TALEN gene-editing platform and in vivo candidates HEAL-101 (APOC3) and HEAL-201 (PCSK9) formulated in lipid nanoparticles.

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